Vasopressors

Dosing

Infusion

Medication	Dose
Norepinephrine	0.01-3 mcg/kg/min
Epinephrine	0.01-1 mcg/kg/min
Dopamine	0.5 - 20 mcg/kg/min
	β1: 5-10 mcg/kg/min
	β1 + α: > 10 mcg/kg/min
Phenylephrine	0.5-4 mcg/kg/min
Vasopressin	0.04 U/min
Dobutamine	2-20 mcg/kg/min

Push Dose

Preparing Push Dose Pressor Syringes, EMCrit Page on Push Dose Pressors

• Phenylephrine 50-200 mcg [For 100 mcg/mL = 0.5 - 2.0 mL]
  • To Prepare 100mcg/mL: 10mg Phenylephrine + 100mL of NS
• Epinephrine 5-20 mcg [For 10 mcg/mL = 0.5 - 2.0mL]¹
  • Never give an ampule of cardiac epinephrine to a patient with a pulse
  • To Prepare 10mcg/mL: 1mL Cardiac Epi (100mcg/mL = 1:10,000) + 9mL NS
• Ephedrine: β1 + indirect α effects, Lasts 1 hour

Footnotes

1. Same concentration as Lidocaine with Epinephrine, so infiltration isn’t a huge risk ↩