MotherToBaby Fact Sheets

MotherToBaby is the public-facing arm of the Organization of Teratology Information Specialists (OTIS). Fact sheets summarize peer-reviewed teratology data for medications, infections, vaccines, recreational drugs, and chemical exposures in pregnancy and lactation. Fact sheets are written and reviewed by teratology specialists; the underlying database (Reprotox / TERIS) is subscription, but the OTIS fact sheets are free.

• MotherToBaby home
• All Fact Sheets (A–Z) — exposures during pregnancy & breastfeeding.
• Counselor service (free, multilingual) — chat, text, phone for clinicians and patients.

High-frequency fact sheets

• Acetaminophen (Tylenol)
• Ibuprofen / NSAIDs
• SSRIs
• Lithium
• Valproic acid — known teratogen.
• Isotretinoin — known teratogen.
• Warfarin — known teratogen.
• ACE inhibitors / ARBs
• Cannabis (marijuana)
• Alcohol
• Caffeine
• COVID-19 / COVID vaccines

Studies database

• MotherToBaby Pregnancy Studies enrollment — observational pregnancy registries for new drugs; clinicians can refer patients.

Other reproductive-toxicology references

• Reprotox (subscription) — sister database of full primary-literature summaries; institutional access common.
• TERIS (subscription) — University of Washington’s teratogen database.
• REPROTOX-affiliated peer-reviewed journal: Birth Defects Research